Study confirms that CBD is beneficial in treating epilepsy

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Ongoing research continues to uncover the health benefits of cannabis

Epilepsy is a chronic disease that affects brain neurons, which present an uncontrolled and improvised electrical activity. According to a recent study, cannabidiol (CBD) could be of great help in coping with epilepsy and its consequences due to its anticonvulsant, antioxidant, anti-inflammatory, and analgesic effects. Many of these patients can now find a better quality of life thanks to the famous cannabis compound.

Epilepsy is diagnosed by the presence of two or more unprovoked seizures, in addition to a careful neurological examination that can record the abnormal electrical pattern and the brain focus of onset of the discharges. Experts have long argued, anecdotally, that products derived from the whole cannabis plant are more effective than those containing isolated forms of CBD, especially when treating this condition.

A group of researchers in Australia has come together to corroborate these claims. The team set out to closely examine the effect of a nutraceutical product, extracted from the Cannabis Sativa L. plant, on sodium-dependent sodium channels and on voltage-dependent sodium channels in epilepsy.

These sodium channels are responsible for initiating action in neurons in the brain, resulting in epileptic seizures. Research continues to indicate that purified or isolated CBD also acts as an inhibitor of these channels, resulting in less frequent seizures.

“Our present findings show that a CBD-dominant hemp-derived product potently inhibited NaV channels [voltage-gated sodium channels],” the authors concluded. “NP [the nutraceutical product] appeared to more potently inhibit NaV channels based on its CBD content than purified CBD, although this could engender both increased therapeutic efficacy and side-effects in epilepsy patients.”