Cannabis found to be beneficial in protecting against neurodegenerative diseases

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The evidence could lead to more use of cannabis for treating Alzheimer’s

The great potential of cannabinoids as therapeutic substances has been demonstrated beyond their analgesic or antiemetic use, that is, in neurodegenerative diseases in which they can not only reduce symptoms but also slow down the disease process. Unprecedented research has found that cannabinol (CBN), a lesser-known cannabis compound, has the ability to potentially help prevent and treat age-related neurodegenerative diseases such as Alzheimer’s disease.

Although it has already become clear that the most studied compounds known to science are cannabidiol (CBD) and tetrahydrocannabinol (THC), many researchers have begun to give special priority to CBN. Although its therapeutic properties are not as well known, a team of Salk researchers has given it sufficient importance and described that CBN has the ability to protect nerve cells from oxidative damage, an important driver of cell death.

With the advent of findings like these, it would not be surprising to see new novel strategies being implemented for CBN to mitigate a variety of neurodegenerative diseases. “We’ve found that cannabinol protects neurons from oxidative stress and cell death, two of the major contributors to Alzheimer’s. This discovery could one day lead to the development of new therapeutics for treating this disease and other neurodegenerative disorders, like Parkinson’s disease,” said Pamela Maher, lead author of the research and research professor and head of the Salk Cellular Neurobiology Laboratory.

According to the results, it was noted that CBN performs its function by protecting mitochondria that feed cells within neurons. Science indicates that oxidation causes mitochondria to curl up like donuts in damaged cells. This change shows up in the aging cells of people suffering from diseases such as Alzheimer’s disease. Through CBN, this has been prevented so that the mitochondria can continue to function properly.